Selective abrogation of antigen-specific human B cell responses by antigen-ricin conjugates.
نویسندگان
چکیده
منابع مشابه
Selective abrogation of antigen-specific human B cell responses by antigen-ricin conjugates
The feasibility of selectively eliminating human antigen-specific B cell responses by treating cells in vitro with antigen covalently linked to a cell toxin was examined. Tetanus toxoid (TT) was conjugated to the toxin ricin via a thioether linkage. Peripheral blood mononuclear cells from recently immunized subjects were preincubated for 2 h with TT-ricin in the presence of lactose. Antigen was...
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ژورنال
عنوان ژورنال: Journal of Experimental Medicine
سال: 1982
ISSN: 0022-1007,1540-9538
DOI: 10.1084/jem.156.2.634